Acti PEA 60 caps. / 400 mg

PEA has a beneficial effect on cognitive skills, overall brain health and its day-to-day functioning. Effects are visible after 30 days and are improved over the next month of supplementation.

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80.00 gr
Product type
Veggie capsules



Acti PEA – about the product 


PEA) is produced in the body to reduce pain and inflammation. The fatty acid can safely increase the natural cannabinoid levels and to protect the nerves through the whole body. There are encouraging beneficial effects in treating diseases and conditions such as depression, Alzheimer's and autoimmune diseases.

Acti PEA is a nutritional supplement without soy, gluten, dairy products and eggs that contains optimal amounts of palmitoylethanolamide (PEA).

Acti PEA - Active Ingredients 

PEA is used as a well-tolerated supplement identified as an anti-inflammatory, analgesic and neuroprotective agent isolated from soy, egg yolk and peanuts.

Many animals and plants produce PEA. The highest amounts can be found in soybean lecithin, soy, egg yolk and others.

PEA has been known since the 1950s and has been the subject of numerous studies. As an endogenous, safe amide of fatty acids, palmitoyl-ethanolamide is used to relieve the condition of diseases of different types.

PEA - mechanism of action 

First of all, effects are not only direct but also indirect through other endogenous molecules such as anandamide and oleoylethanolamide. It causes many biological functions in a completely safe way.

The primary purpose of palmitoyl-ethanolamide is PPAR-alpha (NR1C1). This is a group of receptor proteins that regulate lipid metabolism in the liver and are found in skeletal muscles, kidneys, intestines, adrenal glands and the heart. PEA is also an important part of the body's keto-genesis and anti-inflammatory responses.

PEA is found in the central nervous system, as well as the kidneys, liver and lungs.

Another receptor that is affected by PEA is CB2, which plays an important role in the human immune system. It is located in hematopoietic cells, macrophages and B cells and helps to increase the number of blood cells, eliminates microbes and cancer cells and builds up antibodies. Probably, many of the benefits that PEA exerts on the immune system come from its effects on CB2.

PEA is associated with GPR55 and GPR119. They are considered new cannabinoid receptors. It is believed that they should play an important role in the effects of the endocannabinoid system. GPR55 is found in bone cells and the little brain, while GPR119 located in the pancreas and digestive tract, regulates the feeling of hunger and secretion of incretin and insulin. 

PEA has been identified in the 1950s as a therapeutic substance with powerful anti-inflammatory properties. Since 1970, anti-inflammatory and other immunomodulatory properties of PEA have been established in a number of placebo-controlled double-blind clinical trials on influenza and the common cold.

Acti PEA - purpose

PEA is an effective and completely safe alternative that reduces chronic pain, inflammation and degenerative changes in various pathologies:

  • Neuralgic locomotor pain;
  • Chronic headaches, migraine and occipital neuralgia;
  • Neurodegenerative diseases (Alzheimer's and LAS);
  • Depression;
  • Autoimmune diseases (e.g., MS, fibromyalgia);
  • Infectious diseases.

How does Acti PEA help your health? 

In addition to all these receptors and their advantages against pain, including anti-inflammatory actions, PEA also helps regulate fat and glial cells. That way it controls the immune response, histamine release, allergies, and various autoimmune diseases.

Thanks to PEA, a state of homeostasis can be maintained, protecting neurons and providing nutrients and oxygen to the body.

One of the most important features of Acti PEA is that it is a completely safe food supplement. The palmitoylethanolamide contained in Acti PEA is a completely natural amide of fatty acid and can not be overdosed, does not cause addiction, side effects or allergic reactions.

Acti PEA can also be taken to reduce the pain and inflammation caused by fibromyalgia, endometriosis, arthritis pain, etc.


1 caps.

2 caps.

 3 caps.

Palmitoylethanolamide (PEA)  OptiPEAⓇ

400 mg

800 mg

1200 mg

Excipients: magnesium stearate

Does not contain soy, gluten, dairy, eggs and seafood. Suitable for vegetarians. 

Net weight: 24.48 g

1 to 3 capsules daily, during or after a meal, or as your doctor prescribes. Adjust the dose after 2 months of intake.

Do not exceed the recommended daily dose.

Do not use as a substitute for a varied diet.

Keep in a dry, cool place out of the reach of children.

Not recommended during pregnancy and nursing.

Елеонора Колева 2021-08-26
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