• Irritable bowel;
• Constipation;
• Bloating and chronic stomach pain;
• Arrhythmia;
• Runny nose;
• Migrainous headache;
• Dizziness;
• Attention deficit or hyperactivity disorder in childhood.

Symptoms are often individual and it is difficult to determine the exact cause. Histamine levels can be detected by a histamine intolerance test. Its high levels can be seen as a sign of diaminoxidase deficiency. In such situations, the specialized supplement DAOKids can help balance the levels of the important enzyme and help break down histamine.

DAOKids provides diaminoxidase in an easily absorbed form and ensures high bioavailability of the active ingredient after intake. It reaches the small intestine easily and quickly, where it acts directly to improve histamine breakdown.

It is a good idea to consult a doctor when taking DAOKids in order to prescribe an optimal intake regimen. This will avoid unwanted interactions with certain medicinal products that may inhibit diaminoxidase activity. 

DAOKids® is a specialised dietary supplement that aims to regulate the activity of the enzyme DAO in the small intestine and to aid the breakdown of histamine from ingested food.

Histamine is a major compound that is found in a large number of food products. It performs a number of functions in the body and supports overall health. To reach the tissues and organs where it is needed, histamine must be broken down. Otherwise, it remains in the digestive system and begins to cause health problems. This degradation takes place through digestive enzymes. The enzyme most important for the digestion of histamine is diamine oxidase (DAO).

When this enzyme is in insufficient quantity or its activity is low, histamine cannot be broken down and passes from the intestinal mucosa into the bloodstream, causing adverse symptoms.

Symptoms of DAO deficiency are varied and individual. The most common among them are:

• Migraine or chronic headache;
• Gastrointestinal disorders, especially those associated with irritable bowel syndrome (IBS), such as constipation, diarrhea, flatulence, or bloating;
• Dermatological disorders, such as dry skin, atopy or psoriasis;
• Soft tissue pain, often diagnosed as fibromyalgia;
• Chronic fatigue;
• In childhood and adolescence, DAO deficiency is associated with attention deficit hyperactivity disorder (ADHD).  

More about DAO

DAO catalyzes the oxidative deamination of the primary amino group from histamine to imidazole acetaldehyde, simultaneously producing hydrogen peroxide and ammonia. It is stored in plasma membrane vesicles in epithelial cells of the kidney and intestine and released into the circulation upon various stimulation. It is included in the group of copper amine oxidases, and its active form is the homodimeric with active cofactor 2,4,5-trihydroxyphenylalanine quinone. Its kinetics are 20 µmol/L for histamine, and its optimal functioning is at pH 7.2.

When a deficiency of the enzyme is detected, the patient should start taking DAO from external sources. 

Why trust DAOKids®

DAOKids® is an easily absorbed, bioavailable form of the enzyme. When taken as directed, it readily reaches the small intestine and (along with the already available DAO) aids histamine breakdown.  One capsule of DAOKids® before a meal significantly reduces various health problems.

Origin: Spain